Yang Zhang's Research Group

Yang Zhang
Research Group

The Zhang Lab

University of Kansas
Department of Molecular Biosciences
Center for Bioinformatics
2030 Becker Dr
Lawrence, KS 66047-1620
Phone: (785)864-1948
fax: (785)864-5558
Email: Zhanglab@ku.edu

Research Interests

Bioinformatics
Protein structure prediction
Protein-protein & protein-ligand docking
New drug design
Single molecule mechanics

One of the major projects in our laboratory is to develop novel computational algorithms for the genome-scale and high-resolution prediction of protein structures and protein-ligand interactions. The goal is to annotate the function of proteins based on the sequence-to-structure-to-function paradigm and therefore enhance the impact of genome sequencing on biology and medicine.

Research Highlights

Critical Assessment of Structure Prediction (CASP) is a biennial worldwide competition in protein structure prediction. Our laboratory was quite successful in the recent 7th CASP experiment. The picture shows a distribution of Z-score of the GDT-TS score of all groups in the server section of CASP7.

Service Highlights

As of today, our I-TASSER server has generated 11651 protein structure predictions for 987 registered users from 55 countries in the world.

zhanglab@ku.edu | (785) 864-1948 | 2030 Becker Dr, Lawrence, KS 66047