Yang Zhang
Research Group

Home

Publications

Research

People

Funding

Job openings

Teaching

On-line services:
I-TASSER
LOMETS
MUSTER
TM-score
TM-align
CASP7
CASP8

Downloadable:
Potential
Decoys
SPICKER

I-TASSER potential

Following are the general energy terms used in the I-TASSER modeling:

  • contact_cut.comm: Residue contact cutoff parameters
  • contact_profile.comm: Side-chain contacts environment profile
  • contact3.comm: Orientation-dependent side-chain contact potential
  • CA13.comm: Short-range C-alpha correlation of (i,i+2)
  • CA14.comm: Short-range C-alpha correlation of (i,i+3)
  • CA15.comm: Short-range C-alpha correlation of (i,i+4)
  • CA14s.comm: Short-range C-alpha correlation of (i,i+3) for strands
  • CA14h.comm: Short-range C-alpha correlation of (i,i+3) for helices
  • CA15s.comm: Short-range C-alpha correlation of (i,i+4) for strands
  • CA15h.comm: Short-range C-alpha correlation of (i,i+4) for helices
  • CB.comm: C-beta positions
  • sidechain.comm: Sidechain center positions

    If you have questions about how to use the energy terms, please read the following
    Questions & Answers (09/03/2007).
    Questions & Answers (11/21/2007).
    Questions & Answers (04/19/2008).


    References:
    1. Yang Zhang, Andrzej Kolinski, Jeffrey Skolnick. Touchstone II: A new approach to ab initio protein Structure Prediction. Biophysical Journal, vol 85, 1145 (2003). [PDF]
    2. Yang Zhang, Jeffrey Skolnick. Automated structure prediction of weakly homologous proteins on a genomic scale. Proceedings of the National Academy of Sciences of USA, vol 101, 7594 (2004). [PDF]
    3. Sitao Wu, Jeffrey Skolnick, Yang Zhang. Ab initio modeling of small proteins by iterative TASSER simulations BMC Biology, vol 5, 17 (2007). [PDF]


  • zhanglab@ku.edu | (785) 864-1948 | 2030 Becker Dr, Lawrence, KS 66047